Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998105 | 0.99 | PTGS2 (0.60) | PTGS2 | |
| SCHEMBL6535120 | 0.86 | PTGS2 (0.59) | PTGS2 | |
| SCHEMBL7998144 | 0.85 | PTGS2 (0.59) | PTGS2 | |
| SCHEMBL7998633 | 0.85 | PTGS2 (0.60) | PTGS2 | |
| SCHEMBL8002020 | 0.82 | PTGS2 (0.52) | PTGS2 | |
| SCHEMBL7998103 | 0.81 | PTGS2 (0.52) | PTGS2 | |
| SCHEMBL7998106 | 0.81 | PTGS2 (0.54) | PTGS2 | |
| SCHEMBL6535195 | 0.79 | PTGS2 (0.59) | PTGS2 | |
| SCHEMBL6534985 | 0.78 | PTGS2 (0.47) | PTGS2 | |
| SCHEMBL7994698 | 0.77 | PTGS2 (0.44) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284918-B1 | ENZYME INHIBITORS | VANDERBILT UNIVERSITY | 2001-09-04 | — | — | US | disclosed |