SCHEMBL8002188

SCHEMBL8002188

C=N/C=C\N(C)N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14364243 0.75
SCHEMBL24961187 0.71
SCHEMBL21446112 0.69
SCHEMBL24059291 0.69
SCHEMBL19311478 0.67
SCHEMBL11955021 0.67
SCHEMBL22628814 0.67
SCHEMBL19828477 0.65 TAS2R38 (0.30)
SCHEMBL23230280 0.65
SCHEMBL19772390 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230320112-A1 POLYMERS, FORMULATIONS, ORGANIC OPTOELECTRONIC DEVICES, AND APPLICATIONS THEREOF Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-10-05 US disclosed
WO-2021081881-A1 FUNCTIONAL CARBOHYDRATE MOLECULE BASED ON TDG MOLECULAR SCAFFOLD, AND PREPARATION METHOD THEREFOR 深圳先进技术研究院 2021-05-06 WO disclosed
WO-2021032209-A1 ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF 四川海思科制药有限公司 2021-02-25 WO disclosed
EP-3575298-A1 FUSED HETEROCYCLIC COMPOUND AND COMPOSITION CONTAINING SAME Sumitomo Chemical Company Limited (JP) 2019-12-04 EP disclosed
US-20170240589-A1 COMPOSITIONS AND METHODS FOR TREATING CNS DISORDERS SAGE THERAPEUTICS, INC. 2017-08-24 US disclosed
EP-2311851-A2 Inhibitors of serine proteases, particularly HCV NS3-NS4A protease VERTEX PHARMACEUTICALS INCORPORATED (US) 2011-04-20 EP disclosed
EP-2230254-A2 Anti-IGFR1 antibody therapeutic combinations Schering Corporation (US) 2010-09-22 EP disclosed
EP-1689782-B1 ANTI-IGFR1 ANTIBODY THERAPEUTIC COMBINATIONS SCHERING CORP (US) 2010-04-21 EP disclosed
WO-2009143156-A2 IMIDAZO[1,2-a]PYRIDINE COMPOUNDS SEPRACOR INC. (US) 2009-11-26 WO disclosed
WO-2008141011-A1 5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS AMIRA PHARMACEUTICALS, INC. (US) 2008-11-20 WO disclosed