SCHEMBL8002430

SCHEMBL8002430

CCCC[Sn](CCCC)(CCCC)/C(C(=O)O)=C(/C(=O)O)[Sn](CCCC)(CCCC)CCCC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.39
ALOX15 P16050 2/20 0.38
CA2 P00918 1/20 0.38
MAPK1 P28482 1/20 0.38
GPR84 Q9NQS5 7/20 0.37
PPARG P37231 7/20 0.37
PPARD Q03181 7/20 0.37
PPARA Q07869 7/20 0.37
HDAC11 Q96DB2 5/20 0.37
TSHR P16473 4/20 0.37
PTPN1 P18031 3/20 0.37
ALDH1A1 P00352 2/20 0.37
TLR2 O60603 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
FABP4 P15090 2/20 0.37
SLC22A6 Q4U2R8 1/20 0.37
SLC22A8 Q8TCC7 1/20 0.37
MEN1 O00255 1/20 0.37
ESR1 P03372 1/20 0.37
PDE4A P27815 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL727984 0.79 AKR1B1 (0.42) AKR1B1ALOX15GPR84PPARGPPARD
SCHEMBL6012107 0.76 AKR1B1 (0.36) AKR1B1ALOX15GPR84PPARGPPARD
SCHEMBL5132104 0.76 CES1 (0.41) AKR1B1ALOX15GPR84PPARGPPARD
SCHEMBL11856586 0.75 AKR1B1 (0.39) AKR1B1ALOX15GPR84PPARGPPARD
SCHEMBL16667226 0.75 EP300 (0.36) AKR1B1ALOX15GPR84PPARGPPARD
SCHEMBL3286015 0.75 EP300 (0.36) AKR1B1ALOX15GPR84PPARGPPARD
SCHEMBL16667225 0.75 EP300 (0.36) AKR1B1ALOX15GPR84PPARGPPARD
SCHEMBL18421166 0.74 CES1 (0.40) AKR1B1ALOX15GPR84PPARGPPARD
SCHEMBL29229151 0.72 CES2 (0.38) AKR1B1ALOX15GPR84PPARGPPARD
SCHEMBL7219686 0.72 CA1 (0.38) AKR1B1ALOX15CA2GPR84PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7228564-A None JP disclosed
US-6042893-A ELECTRODEPOSITION OF CURABLE CATIONIC POLYMER ONTO ELECTROCONDUCTIVE SUBSTRATE IMMERSED IN BATH CONTAINING RESIN AND ORGANOMETALLIC POLYMERIZATION CATALYST MIXTURE ELF ATOCHEM NORTH AMERICA INC. (US) 2000-03-28 US disclosed
US-6028128-A Metal containing E-coat catalysts optionally with tin catalysts ELF ATOCHEM NORTH AMERICA, INC. (US) 2000-02-22 US disclosed
US-6001900-A CURABLE COATING WITH BLOCKED ISOCYANATE OR BLOCKED ISOTHIOCYANATE AND ACTIVE HYDROGEN COMPOUND AND REACTION OF ORGANOTIN COMPOUND ELF ATOCHEM NORTH AMERICA, INC. (US) 1999-12-14 US disclosed
US-5910373-A PROMOTION OF LOW TEMPERATURE CURE OF BLOCKED ISOCYANATES AND BLOCKED ISOTHIOCYANATES ELF ATOCHEM NORTH AMERICA, INC. (US) 1999-06-08 US disclosed
US-5859165-A FOR PROMOTING THE REACTION OF A REACTIVE COMPONENT WITH A BLOCKED ISOCYANATE COMPRISING THE REACTION PRODUCT OF A METAL CATALYST, A TRIORGANOTIN COMPOUND AND A MERCAPTAN ELF ATOCHEM NORTH AMERICA, INC. (US) 1999-01-12 US disclosed
JP-H07228564-A PRODUCTION OF CYANOACETIC ESTER NITTO CHEM IND CO LTD 1995-08-29 JP disclosed
US-4526932-A Copolymer containing N-coordinated triorganotin compound NITTO KASEI CO., LTD. (JP) 1985-07-02 US disclosed
US-4389460-A ORGANOTIN UNIT GRAFTED TO CONJUGATED DIENE INSTITUT FRANCAIS DU PETROLE (FR) 1983-06-21 US disclosed
US-4080468-A INSECTICIDES CIBA-GEIGY CORPORATION (US) 1978-03-21 US disclosed
US-4023969-A Deformable elastomer imaging member employing an internal opaque deformable metallic layer XEROX CORPORATION (US) 1977-05-17 US disclosed