Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | ALPG | P10696 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8012290 | 0.77 | KMT2A (0.52) | SMN1; SMN2TSHRALPGKMT2AHSD17B10 | |
| SCHEMBL8008741 | 0.74 | MAPT (0.57) | SMN1; SMN2TSHRKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL7993110 | 0.73 | POLB (0.69) | SMN1; SMN2TSHRKMT2AMAPTMEN1 | |
| SCHEMBL4758531 | 0.71 | MAPT (0.46) | SMN1; SMN2TSHRALPGKMT2AHSD17B10 | |
| SCHEMBL13401381 | 0.71 | HPGD (1.00) | SMN1; SMN2TSHRKMT2AHSD17B10MAPT | |
| SCHEMBL11245223 | 0.70 | HPGD (0.80) | SMN1; SMN2TSHRKMT2AHSD17B10MAPT | |
| SCHEMBL9873632 | 0.70 | NPC1 (0.53) | TSHRKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL4790828 | 0.69 | MAPT (0.49) | SMN1; SMN2TSHRALPGKMT2AHSD17B10 | |
| SCHEMBL27654437 | 0.69 | HPGD (0.49) | SMN1; SMN2TSHRALPGKMT2AHSD17B10 | |
| SCHEMBL4923135 | 0.68 | HPGD (0.76) | SMN1; SMN2TSHRKMT2AHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294572-B1 | USED IN DRUGS; PHSYSICAL PROPERTIES | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2001-09-25 | — | — | US | disclosed |