Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9475577 | 0.85 | HPGD (0.52) | MAPTALDH1A1HTTNPSR1TP53 | |
| SCHEMBL7993110 | 0.79 | POLB (0.69) | MAPTHTTTP53MEN1KMT2A | |
| SCHEMBL9857450 | 0.75 | GRM2 (0.45) | MAPTALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL8002453 | 0.74 | SMN1; SMN2 (0.62) | MAPTALDH1A1HTTNPSR1TP53 | |
| SCHEMBL11120964 | 0.73 | NPC1 (0.60) | MAPTALDH1A1HTTNPSR1TP53 | |
| SCHEMBL4759824 | 0.73 | GRM2 (0.43) | MAPTALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL10668856 | 0.72 | TP53 (0.52) | ALDH1A1TP53SMN1; SMN2CYP1A2GAA | |
| SCHEMBL15937242 | 0.72 | HTT (0.49) | ALDH1A1HTTMEN1KMT2AKDM4E | |
| SCHEMBL10669535 | 0.72 | HPGD (0.52) | MAPTALDH1A1HTTNPSR1TP53 | |
| SCHEMBL10662829 | 0.72 | TP53 (0.59) | ALDH1A1NPSR1TP53SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000015231-A9 | ADENOSINE A3 RECEPTOR MODULATORS | MEDCO RES INC (US) | 2000-08-17 | — | — | WO | disclosed |