⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8017983 | 0.87 | ELANE (0.33) | — | |
| SCHEMBL8013206 | 0.86 | — | — | |
| SCHEMBL10824260 | 0.77 | — | — | |
| SCHEMBL9221125 | 0.77 | ELANE (0.32) | — | |
| SCHEMBL8002509 | 0.74 | — | — | |
| SCHEMBL6399063 | 0.73 | CTSL (0.33) | — | |
| SCHEMBL6399660 | 0.73 | CTSL (0.33) | — | |
| SCHEMBL9428568 | 0.72 | ELANE (0.30) | — | |
| SCHEMBL8010840 | 0.70 | — | — | |
| SCHEMBL5857820 | 0.69 | ELANE (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051569-A | 1'S, 5R, 6R-carbapenem derivatives and antimicrobial agents comprising the same | SUNTORY LIMITED (JP) | 2000-04-18 | — | — | US | disclosed |
| EP-0826687-A1 | Carbapenem derivatives and antimicrobial agents comprising the same | SUNTORY LIMITED (JP) | 1998-03-04 | — | — | EP | disclosed |