Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MVD | P53602 | 1/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998419 | 0.90 | MVD (0.38) | GMNNTP53POLBMAPTTHRB | |
| SCHEMBL7882568 | 0.83 | CYP2D6 (0.38) | GMNNTP53POLBMAPTTHRB | |
| SCHEMBL14445604 | 0.78 | CYP3A4 (0.47) | CYP3A4GAALPAR3LPAR1LPAR2 | |
| SCHEMBL7989596 | 0.76 | CYP2D6 (0.41) | GMNNTP53POLBMAPTTHRB | |
| SCHEMBL7990050 | 0.73 | CYP2D6 (0.38) | GMNNTP53POLBMAPTTHRB | |
| SCHEMBL19595699 | 0.72 | CYP3A4 (0.56) | CYP3A4GAALPAR3LPAR1LPAR2 | |
| SCHEMBL11799423 | 0.68 | CYP3A4 (0.47) | CYP3A4GAALPAR3LPAR1LPAR2 | |
| SCHEMBL10831955 | 0.68 | CYP3A4 (0.56) | CYP3A4GAALPAR3LPAR1LPAR2 | |
| SCHEMBL4449162 | 0.68 | CYP3A4 (0.56) | CYP3A4GAALPAR3LPAR1LPAR2 | |
| Phosphoric Acid SCHEMBL4891241 | 0.68 | GMNN (0.44) | GMNNTP53POLBMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944635-A4 | DIPHOSPHONATE THERAPEUTIC COMPOUNDS | ELIZANOR BIOPHARMACEUTICALS IN (US) | 2000-07-05 | — | — | EP | claimed |
| EP-0944635-A1 | DIPHOSPHONATE THERAPEUTIC COMPOUNDS | Elizanor Biopharmaceuticals, Inc. (US) | 1999-09-29 | — | — | EP | claimed |
| WO-1998015560-A1 | DIPHOSPHONATE THERAPEUTIC COMPOUNDS | ELIZANOR BIOPHARMACEUTICALS, INC. (US) | 1998-04-16 | — | — | WO | claimed |