Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3313487 | 0.80 | POLB (0.43) | CYP3A4GAATSHR | |
| SCHEMBL8002512 | 0.78 | GMNN (0.42) | CYP3A4LPAR3LPAR1LPAR2GAA | |
| SCHEMBL19595699 | 0.78 | CYP3A4 (0.56) | CYP3A4LPAR3LPAR1LPAR2GAA | |
| SCHEMBL7148541 | 0.76 | LPAR3 (0.49) | LPAR3LPAR1LPAR2GPR84MMP9 | |
| SCHEMBL7153050 | 0.76 | LPAR3 (0.49) | LPAR3LPAR1LPAR2GPR84MMP9 | |
| SCHEMBL7152612 | 0.76 | LPAR3 (0.49) | LPAR3LPAR1LPAR2GPR84MMP9 | |
| SCHEMBL11799423 | 0.74 | CYP3A4 (0.47) | CYP3A4LPAR3LPAR1LPAR2GAA | |
| SCHEMBL4449162 | 0.74 | CYP3A4 (0.56) | CYP3A4LPAR3LPAR1LPAR2GAA | |
| SCHEMBL10831955 | 0.74 | CYP3A4 (0.56) | CYP3A4LPAR3LPAR1LPAR2GAA | |
| SCHEMBL11688744 | 0.74 | CYP3A4 (0.42) | CYP3A4LPAR3LPAR1LPAR2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096703-A2 | PHOSPHONATED RIFAMYCINS AND USES THEREOF FOR THE PREVENTION AND TREATMENT OF BONE AND JOINT INFECTIONS | TARGANTA THERAPEUTICS INC. (CA) | 2007-08-30 | — | — | WO | disclosed |