Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7689805 | 0.85 | TSHR (0.39) | ALDH1A1MAPTTSHRSIGMAR1 | |
| SCHEMBL68972 | 0.83 | TSHR (0.35) | ALDH1A1TSHRSIGMAR1 | |
| SCHEMBL8158086 | 0.81 | TSHR (0.34) | ALDH1A1TSHRSIGMAR1 | |
| SCHEMBL8151431 | 0.81 | USP2 (0.39) | USP2ALDH1A1CYP3A4MAPTHPGD | |
| Bromide SCHEMBL11209556 | 0.76 | NFKB1 (0.38) | TSHRNFKB1CYP2C19 | |
| SCHEMBL69489 | 0.74 | TSHR (0.31) | TSHRNFKB1CYP2C19 | |
| SCHEMBL10081536 | 0.74 | USP2 (0.53) | USP2ALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL15027430 | 0.74 | USP2 (0.53) | USP2ALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL517696 | 0.74 | USP2 (0.53) | USP2ALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL4012822 | 0.74 | USP2 (0.53) | USP2ALDH1A1CYP3A4MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000015613-A1 | METHOD OF MAKING TERTIARY HINDERED AMINES | ARISTECH CHEMICAL CORPORATION (US) | 2000-03-23 | — | — | WO | disclosed |