SCHEMBL8002568

SCHEMBL8002568

COc1ccc(N(c2ccccc2)c2ccccc2)c(C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
TSHR P16473 1/20 0.47
GAA P10253 1/20 0.47
CYP1A2 P05177 1/20 0.42
CYP2A6 P11509 1/20 0.42
PTGIR P43119 1/20 0.41
NPC1 O15118 2/20 0.40
ALDH1A1 P00352 2/20 0.40
RAB9A P51151 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
MAPT P10636 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CA4 P22748 1/20 0.40
KDM1A O60341 1/20 0.40
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
LTA4H P09960 1/20 0.39
CSF1R P07333 2/20 0.39
GRIK2 Q13002 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10064631 0.97 MEN1 (0.45) MEN1KMT2ATSHRGAACYP1A2
SCHEMBL1673428 0.94 MEN1 (0.43) MEN1KMT2ATSHRGAACYP1A2
SCHEMBL2734807 0.94 MEN1 (0.43) MEN1KMT2ATSHRGAACYP1A2
SCHEMBL29511979 0.94 MEN1 (0.43) MEN1KMT2ATSHRGAACYP1A2
SCHEMBL14163849 0.92 MEN1 (0.42) MEN1KMT2ATSHRGAACYP1A2
SCHEMBL13152130 0.90 CYP11B1 (0.43) MEN1KMT2ATSHRGAACYP1A2
SCHEMBL8944053 0.89 CA12 (0.47) MEN1KMT2ATSHRGAACYP1A2
SCHEMBL12463495 0.89 KMT2A (0.40) MEN1KMT2ATSHRGAAPTGIR
SCHEMBL8944108 0.89 CA1 (0.42) GAACYP1A2CYP2A6GRIK2ACHE
SCHEMBL3073105 0.89 MEN1 (0.42) MEN1KMT2ATSHRGAACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200117106-A1 COMPOUND MIXTURE, ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER AND PRODUCTION METHOD FOR COMPOUND MIXTURE KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2020-04-16 US disclosed
US-6060206-A Photo- and heat-sensitive recording material and colorant produced from the material FUJI PHOTO FILM CO., LTD. (JP) 2000-05-09 US disclosed