SCHEMBL8944108

SCHEMBL8944108

COc1ccc(N(c2ccc(OC)cc2)c2ccc(OC)cc2C)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
CA12 O43570 2/20 0.42
CA7 P43166 2/20 0.42
CA9 Q16790 2/20 0.42
CA14 Q9ULX7 2/20 0.42
KEAP1 Q14145 2/20 0.42
NFE2L2 Q16236 2/20 0.42
ACHE P22303 2/20 0.41
SLC2A1 P11166 1/20 0.39
CRHR1 P34998 1/20 0.39
GAA P10253 1/20 0.39
TUBB1 Q9H4B7 2/20 0.38
FFAR4 Q5NUL3 1/20 0.38
EGFR P00533 2/20 0.37
PDGFRB P09619 2/20 0.37
KDR P35968 2/20 0.37
TUBB4A P04350 1/20 0.37
TUBB P07437 1/20 0.37
TUBA3C P0DPH7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10064631 0.90 MEN1 (0.45) KEAP1NFE2L2GAACYP1A2CYP2A6
SCHEMBL13152156 0.89 NPC1 (0.39) KEAP1NFE2L2CRHR1GAAGRIK1
SCHEMBL8002568 0.89 MEN1 (0.47) KEAP1NFE2L2ACHEGAACYP1A2
SCHEMBL13152130 0.87 CYP11B1 (0.43) KEAP1NFE2L2GAACYP1A2CYP2A6
SCHEMBL2734807 0.87 MEN1 (0.43) KEAP1NFE2L2GAACYP1A2CYP2A6
SCHEMBL29511979 0.87 MEN1 (0.43) KEAP1NFE2L2GAACYP1A2CYP2A6
SCHEMBL1673428 0.87 MEN1 (0.43) KEAP1NFE2L2GAACYP1A2CYP2A6
SCHEMBL16482185 0.86 CA1 (0.44) CA1CA2CA12CA7CA9
SCHEMBL10057771 0.86 DYRK1A (0.44) CA1CA2CA12CA7CA9
SCHEMBL13152161 0.85 MEN1 (0.38) CA1CA2GAACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed