Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 18/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8018900 | 0.84 | BDKRB2 (0.47) | BDKRB2 | |
| SCHEMBL7012195 | 0.82 | BDKRB2 (0.55) | BDKRB2CYP3A4 | |
| SCHEMBL8002769 | 0.81 | BDKRB2 (0.51) | BDKRB2CYP3A4 | |
| SCHEMBL8554602 | 0.75 | BDKRB2 (0.55) | BDKRB2 | |
| SCHEMBL8015041 | 0.71 | BDKRB2 (0.59) | BDKRB2 | |
| SCHEMBL8015038 | 0.71 | BDKRB2 (0.59) | BDKRB2 | |
| SCHEMBL8018457 | 0.71 | BDKRB2 (0.55) | BDKRB2 | |
| SCHEMBL8014941 | 0.71 | BDKRB2 (0.57) | BDKRB2 | |
| SCHEMBL8014944 | 0.71 | BDKRB2 (0.74) | BDKRB2 | |
| SCHEMBL8014946 | 0.71 | BDKRB2 (0.74) | BDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6015818-A | TREATING KIDNEY, BRAIN, AND CARDIOVASCULAR DISORDERS; HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-01-18 | — | — | US | disclosed |
| EP-0879233-A1 | CHINOLINE AND BENZIMIDAZOLE DERIVATIVES AS BRADYKININ AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-25 | — | — | EP | disclosed |
| WO-1997028153-A1 | CHINOLINE AND BENZIMIDAZOLE DERIVATIVES AS BRADYKININ AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-07 | — | — | WO | disclosed |