Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28430957 | 0.79 | TSHR (0.45) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL5028823 | 0.72 | TSHR (0.40) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL29136240 | 0.71 | TSHR (0.42) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL2713693 | 0.69 | TSHR (0.38) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL704975 | 0.69 | TSHR (0.42) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL216519 | 0.68 | TSHR (0.41) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL28060791 | 0.67 | TSHR (0.50) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL8655279 | 0.67 | TSHR (0.38) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL27847987 | 0.67 | TSHR (0.49) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL27501921 | 0.67 | TSHR (0.49) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972223-A4 | LIGHT FILTERING CONTACT LENS | PARAGON VISION SCIENCES INC (US) | 2000-07-19 | — | — | EP | disclosed |
| EP-0972223-A1 | LIGHT FILTERING CONTACT LENS | PARAGON VISION SCIENCES, INC. (US) | 2000-01-19 | — | — | EP | disclosed |
| US-5846457-A | Light filtering contact lens method | SPORTSIGHT, LLC | 1998-12-08 | — | — | US | disclosed |
| WO-1998044380-A1 | LIGHT FILTERING CONTACT LENS | PARAGON VISION SCIENCES, INC. (US) | 1998-10-08 | — | — | WO | disclosed |
| US-5617154-A | Light filtering contact lens | FLEXLENS (US) | 1997-04-01 | — | — | US | disclosed |