Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL216519 | 0.85 | TSHR (0.41) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL9411490 | 0.83 | ALDH1A1 (0.38) | TSHRTHRBALDH1A1 | |
| SCHEMBL712919 | 0.83 | TSHR (0.43) | TSHRTHRBALDH1A1 | |
| SCHEMBL17049379 | 0.80 | — | — | |
| SCHEMBL8655279 | 0.79 | TSHR (0.38) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Acrylamide SCHEMBL28093276 | 0.78 | TSHR (0.35) | TSHRTHRB | |
| SCHEMBL28060791 | 0.77 | TSHR (0.50) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL27148948 | 0.75 | TSHR (0.40) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL27819753 | 0.74 | TSHR (0.53) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL5028823 | 0.74 | TSHR (0.40) | TSHRTHRBALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9795541-B2 | Use of free radically curable compositions in additive manufacturing methods | VOCO GMBH (DE) | 2017-10-24 | — | — | US | claimed |
| EP-2024406-B1 | A SILICONE ACRYLATE HYBRID COMPOSITION | DOW CORNING (US) | 2012-08-01 | — | — | EP | claimed |
| US-20090196911-A1 | Silicone Acrylate Hybride Composition and Method Of Making Same | DOW SILICONES CORPORATION | 2009-08-06 | — | — | US | claimed |
| EP-1940368-A2 | TRANSDERMAL DRUG DELIVERY SYSTEM WITH ACRYLATE OR METHACRYLATE FUNCTIONAL PRESSURE SENSITIVE ADHESIVE COMPOSITION | DOW CORNING CORPORATION (US) | 2008-07-09 | — | — | EP | claimed |
| WO-2007145996-A9 | A SILICONE ACRYLATE HYBRID COMPOSITION | DOW CORNING (US) | 2008-02-14 | — | — | WO | claimed |
| WO-2007050580-A2 | TRANSDERMAL DRUG DELIVERY SYSTEM WITH ACRYLATE OR METHACRYLATE FUNCTIONAL PRESSURE SENSITIVE ADHESIVE COMPOSITION | DOW CORNING CORPORATION (US) | 2007-05-03 | — | — | WO | claimed |
| EP-0295947-B1 | Gas permeable contact lens and method and materials for its manufacture | OCULAR TECHNOLOGIES INC (US) | 1994-12-21 | — | — | EP | claimed |
| EP-0455585-B1 | Unsaturated urea polysiloxanes | CIBA GEIGY AG (CH) | 1994-03-23 | — | — | EP | claimed |
| US-5162469-A | Copolymer of Fluoromonomer and Hydrophobic Hydrolyzable Silicone Monomer | OPTICAL RESEARCH INC. (US) | 1992-11-10 | — | — | US | claimed |
| EP-0455585-A1 | Unsaturated urea polysiloxanes | CIBA-GEIGY AG (CH) | 1991-11-06 | — | — | EP | claimed |
| US-4820747-A | ACRYLATED CROSSLINKED POLYSILOXANES FORM HARD, HYDROPHILIC, DISPOSABLE, EXTENDED-WEAR LENSES | OCULAR TECHNOLOGIES, INC. (US) | 1989-04-11 | — | — | US | claimed |
| EP-0295947-A2 | Gas permeable contact lens and method and materials for its manufacture | OCULAR TECHNOLOGIES INC. (US) | 1988-12-21 | — | — | EP | claimed |
| EP-3256504-B1 | MULTI-PHASE SILICONE ACRYLIC HYBRID VISCO-ELASTIC COMPOSITIONS AND METHODS OF MAKING SAME | DOW SILICONES CORP (US) | 2020-06-24 | — | — | EP | disclosed |
| US-10316228-B2 | Multi-phase silicone acrylic hybrid visco-elastic compositions and methods of making same | DOW SILICONES CORPORATION (US) | 2019-06-11 | — | — | US | disclosed |
| US-9946158-B2 | Composition for forming resist underlayer film for nanoimprint | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2018-04-17 | — | — | US | disclosed |
| EP-2461350-B1 | USE OF A COMPOSITION FOR FORMING RESIST UNDERLAYER FILM FOR NANOIMPRINT LITHOGRAPHY | NISSAN CHEMICAL IND LTD (JP) | 2018-02-28 | — | — | EP | disclosed |
| WO-1992018548-A1 | NOVEL COMPOSITION FOR CONTACT LENSES | OPTICAL RESEARCH, INC. (US) | 1992-10-29 | — | — | WO | disclosed |
| EP-0493320-A2 | Fluorine and/or Silicone containing poly(alkylene-oxide)-block copolymer hydrogels and contact lenses thereof | CIBA-GEIGY AG (CH) | 1992-07-01 | — | — | EP | disclosed |
| US-5081164-A | Organosilicon dental composite restorative materials | LAI LABORATORIES, INC. (US) | 1992-01-14 | — | — | US | disclosed |
| EP-0455585-A1 | Unsaturated urea polysiloxanes | CIBA-GEIGY AG (CH) | 1991-11-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090196911-A1 | Silicone Acrylate Hybride Composition and Method Of Making Same | MMS19, CAD, ACR | TSHR 4760/4885THRB 4098/4885ALDH1A1 2679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.