Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 7/20 | 0.76 |
| ▸ | TNF | P01375 | 4/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.76 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.76 |
| ▸ | ACHE | P22303 | 2/20 | 0.76 |
| ▸ | PDE4A | P27815 | 2/20 | 0.76 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.76 |
| ▸ | USP2 | O75604 | 1/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.76 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.76 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.76 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.76 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.76 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9122781 | 0.99 | ADORA2B (0.74) | ADORA2BTNFLMNACYP1A2NFKB1 | |
| SCHEMBL9123779 | 0.90 | ADORA2B (0.79) | ADORA2BTNFLMNACYP1A2NFKB1 | |
| SCHEMBL16730548 | 0.89 | ADORA2B (0.77) | ADORA2BTNFLMNACYP1A2NFKB1 | |
| SCHEMBL10522346 | 0.88 | ADORA2B (0.76) | ADORA2BTNFLMNACYP1A2NFKB1 | |
| SCHEMBL11301985 | 0.88 | ADORA2B (0.79) | ADORA2BTNFLMNACYP1A2NFKB1 | |
| SCHEMBL9122988 | 0.87 | ADORA2B (0.74) | ADORA2BTNFLMNACYP1A2NFKB1 | |
| SCHEMBL9123285 | 0.87 | ADORA2B (0.74) | ADORA2BTNFLMNACYP1A2NFKB1 | |
| SCHEMBL8686059 | 0.87 | ADORA2B (0.74) | ADORA2BTNFLMNACYP1A2NFKB1 | |
| SCHEMBL9123835 | 0.87 | ADORA2B (0.74) | ADORA2BTNFLMNACYP1A2NFKB1 | |
| Pentoxifylline SCHEMBL3986204 | 0.86 | ADORA2B (1.00) | ADORA2BTNFLMNACYP1A2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670506-A | ANTIINFLAMMATORY AGENTS, FUNGICIDES, MICROBIOCIDES | CELL THERAPEUTICS, INC. (US) | 1997-09-23 | — | — | US | claimed |
| EP-0739203-A4 | METHOD FOR TREATING DISEASES MEDIATED BY CELLULAR PROLIFERATION IN RESPONSE TO PDGF, EGF, FGF AND VEGF | CELL THERAPEUTICS INC (US) | 2000-12-20 | — | — | EP | disclosed |
| US-5929081-A | ADMINISTERING COMPOUND THAT INHIBITS SIGNAL TRANSDUCTION THROUGH CELLULAR ACCUMULATION OF NON-ARACHIDONYL PHOSPHATIDIC ACID | CELL THERAPEUTICS INC. (US) | 1999-07-27 | — | — | US | disclosed |
| US-5859018-A | ANTIARTHRITIC AGENTS; ANTITUMOR AGENTS; CARDIOVASCULAR DISORDERS | CELL THERAPEUTICS, INC. (US) | 1999-01-12 | — | — | US | disclosed |
| US-5795898-A | ANTITUMOR, ANTICANCER AGENTS, ANTIDIABETIC AGENTS, SKIN DISORDERS | CELL THERAPEUTICS, INC. (US) | 1998-08-18 | — | — | US | disclosed |
| US-5670506-A | ANTIINFLAMMATORY AGENTS, FUNGICIDES, MICROBIOCIDES | CELL THERAPEUTICS, INC. (US) | 1997-09-23 | — | — | US | disclosed |
| EP-0739203-A1 | METHOD FOR TREATING DISEASES MEDIATED BY CELLULAR PROLIFERATION IN RESPONSE TO PDGF, EGF, FGF AND VEGF | CELL THERAPEUTICS, INC. (US) | 1996-10-30 | — | — | EP | disclosed |
| EP-0714302-A4 | THERAPEUTIC COMPOUNDS | CELL THERAPEUTICS INC (US) | 1996-10-09 | — | — | EP | disclosed |
| EP-0714302-A1 | THERAPEUTIC COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995020589-A1 | CELL SIGNALING INHIBITORS | CELL THERAPEUTICS, INC. (US) | 1995-08-03 | — | — | WO | disclosed |
| WO-1995019171-A1 | METHOD FOR TREATING DISEASES MEDIATED BY CELLULAR PROLIFERATION IN RESPONSE TO PDGF, EGF, FGF AND VEGF | CELL THERAPEUTICS, INC. (US) | 1995-07-20 | — | — | WO | disclosed |
| WO-1994022449-A1 | THERAPEUTIC COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-10-13 | — | — | WO | disclosed |