Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 2/20 | 0.45 |
| ▸ | GJA1 | P17302 | 1/20 | 0.45 |
| ▸ | SSTR4 | P31391 | 5/20 | 0.45 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.43 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.43 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.41 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.41 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.41 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.41 |
| ▸ | TACR2 | P21452 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8002977 | 0.92 | GJB2 (0.45) | GJB2GJA1SSTR4SLC5A1SLC5A2 | |
| SCHEMBL5941739 | 0.87 | SSTR4 (0.44) | GJB2GJA1SSTR4SSTR5SSTR1 | |
| SCHEMBL7452769 | 0.85 | SLC5A2 (0.40) | GJB2GJA1SLC5A1SLC5A2SSTR5 | |
| SCHEMBL7997389 | 0.85 | SLC5A2 (0.40) | GJB2GJA1SLC5A1SLC5A2SSTR5 | |
| SCHEMBL7552425 | 0.85 | SLC5A2 (0.40) | GJB2GJA1SLC5A1SLC5A2SSTR5 | |
| SCHEMBL7555790 | 0.85 | SLC5A2 (0.40) | GJB2GJA1SLC5A1SLC5A2SSTR5 | |
| SCHEMBL7999781 | 0.84 | GJB2 (0.38) | GJB2GJA1SSTR4SLC5A1SLC5A2 | |
| SCHEMBL8907486 | 0.84 | GJB2 (0.47) | GJB2GJA1SSTR4SLC5A1SLC5A2 | |
| SCHEMBL5689122 | 0.83 | GJB2 (0.48) | GJB2GJA1SSTR4SSTR5SSTR1 | |
| SCHEMBL5688991 | 0.83 | SSTR4 (0.47) | GJB2SSTR4SSTR5SSTR1SSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6040433-A | Sulfinyl hexose derivatives useful for glycosylation | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2000-03-21 | — | — | US | disclosed |
| EP-0901629-A4 | CARBOHYDRATE-BASED LIGAND LIBRARY, ASSAY AND METHOD | UNIV PRINCETON (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0901629-A1 | CARBOHYDRATE-BASED LIGAND LIBRARY, ASSAY AND METHOD | PRINCETON UNIVERSITY (US) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997035202-A1 | CARBOHYDRATE-BASED LIGAND LIBRARY, ASSAY AND METHOD | PRINCETON UNIVERSITY (US) | 1997-09-25 | — | — | WO | disclosed |