Ethylene Glycol

Ethylene Glycol

SCHEMBL8003023

CCCCCCCCCCCCCCCCCC(=O)OP(=O)(O)O.OCCO

nearest known ligand 0.50

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 7/20 0.50
ENPP2 Q13822 6/20 0.50
LPAR1 Q92633 5/20 0.50
LPAR2 Q9HBW0 3/20 0.50
LPAR6 P43657 1/20 0.50
LPAR4 Q99677 1/20 0.50
LPAR5 Q9H1C0 1/20 0.50
DGKA P23743 1/20 0.50
MAPT P10636 1/20 0.49
MAPK1 P28482 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.48
LMNA P02545 2/20 0.47
PAM P19021 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL28820001 1.00 LPAR3 (0.50) LPAR3ENPP2LPAR1LPAR2LPAR6
SCHEMBL6742161 0.94 DGKA (0.55) LPAR3ENPP2LPAR1LPAR2LPAR6
SCHEMBL9841015 0.94 DGKA (0.55) LPAR3ENPP2LPAR1LPAR2LPAR6
SCHEMBL2935139 0.94 DGKA (0.55) LPAR3ENPP2LPAR1LPAR2LPAR6
SCHEMBL10771757 0.94 DGKA (0.55) LPAR3ENPP2LPAR1LPAR2LPAR6
SCHEMBL380302 0.94 DGKA (0.55) LPAR3ENPP2LPAR1LPAR2LPAR6
SCHEMBL380922 0.94 DGKA (0.55) LPAR3ENPP2LPAR1LPAR2LPAR6
SCHEMBL339276 0.94 DGKA (0.55) LPAR3ENPP2LPAR1LPAR2LPAR6
SCHEMBL4605602 0.94 DGKA (0.55) LPAR3ENPP2LPAR1LPAR2LPAR6
SCHEMBL669206 0.94 DGKA (0.55) LPAR3ENPP2LPAR1LPAR2LPAR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1011609-A4 COMPOSITIONS FOR COSMETIC APPLICATIONS MEDLOGIC GLOBAL CORP (US) 2000-08-16 EP disclosed
EP-1011609-A1 COMPOSITIONS FOR COSMETIC APPLICATIONS MedLogic Global Corporation (US) 2000-06-28 EP disclosed
WO-1998050005-A1 COMPOSITIONS FOR COSMETIC APPLICATIONS MEDLOGIC GLOBAL CORPORATION (US) 1998-11-12 WO disclosed