SCHEMBL8003210

SCHEMBL8003210

CCCCCCCCCCCC(=O)OP(=O)(O)OP(=O)(O)OP(=O)(O)O.[NaH]

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 6/20 0.52
LPAR1 Q92633 5/20 0.52
ENPP2 Q13822 6/20 0.46
LPAR6 P43657 1/20 0.46
LPAR4 Q99677 1/20 0.46
LPAR5 Q9H1C0 1/20 0.46
LPAR2 Q9HBW0 1/20 0.46
DGKA P23743 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
LMNA P02545 2/20 0.42
PAM P19021 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30826113 0.95 LPAR3 (0.56) LPAR3LPAR1ENPP2LPAR6LPAR4
SCHEMBL29008918 0.95 LPAR3 (0.56) LPAR3LPAR1ENPP2LPAR6LPAR4
SCHEMBL31514330 0.93 LPAR3 (0.54) LPAR3LPAR1ENPP2LPAR6LPAR4
SCHEMBL10939961 0.90 DGKA (0.48) LPAR3LPAR1ENPP2LPAR6LPAR4
SCHEMBL1001203 0.88 LPAR3 (0.48) LPAR3LPAR1ENPP2LPAR6LPAR4
SCHEMBL10478921 0.86 LPAR1 (0.55) LPAR3LPAR1ENPP2LPAR6LPAR4
SCHEMBL10703309 0.84 DGKA (0.55) LPAR3LPAR1ENPP2LPAR6LPAR4
SCHEMBL3924198 0.84 DGKA (0.55) LPAR3LPAR1ENPP2LPAR6LPAR4
SCHEMBL18409606 0.84 DGKA (0.55) LPAR3LPAR1ENPP2LPAR6LPAR4
SCHEMBL3422445 0.84 DGKA (0.55) LPAR3LPAR1ENPP2LPAR6LPAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1011609-A4 COMPOSITIONS FOR COSMETIC APPLICATIONS MEDLOGIC GLOBAL CORP (US) 2000-08-16 EP disclosed
EP-1011609-A1 COMPOSITIONS FOR COSMETIC APPLICATIONS MedLogic Global Corporation (US) 2000-06-28 EP disclosed
WO-1998048768-A9 COMPOSITIONS FOR COSMETIC APPLICATIONS MEDLOGIC GLOBAL CORP (US) 1999-03-25 WO disclosed
WO-1998050005-A1 COMPOSITIONS FOR COSMETIC APPLICATIONS MEDLOGIC GLOBAL CORPORATION (US) 1998-11-12 WO disclosed