Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | DHFR | P00374 | 7/20 | 0.44 |
| ▸ | GART | P22102 | 2/20 | 0.44 |
| ▸ | ATIC | P31939 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 4/20 | 0.43 |
| ▸ | SLC19A1 | P41440 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30076811 | 1.00 | TYMS (0.65) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL6389507 | 0.91 | TYMS (0.69) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL9853745 | 0.87 | TYMS (0.71) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL2577686 | 0.87 | TYMS (0.70) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL30293737 | 0.87 | TYMS (0.70) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL440460 | 0.87 | TYMS (0.70) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL7758365 | 0.85 | TYMS (0.68) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL30887631 | 0.85 | TYMS (0.68) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL8375155 | 0.85 | TYMS (0.68) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL17732194 | 0.85 | TYMS (0.67) | TYMSKDM4EMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080591-A | USEFUL IN BIOLOGICAL ASSAYS FOR DETERMINATION OF VITAMIN B12, FOLATE, CORTISOL, ESTRADIOL, AND THROMBOXANE B2 | BAYER CORPORATION (US) | 2000-06-27 | — | — | US | disclosed |
| US-5663074-A | INCUBATION OF FOLATE WITH AMINE REACTIVE COMPOUND, ACTIVATION AND INCUBATION THE ACRIDINIUM ESTER-FOLATE CONJUGATE | CHIRON DIAGNOSTICS CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
| US-5538901-A | ANALYSIS | CIBA CORNING DIAGNOSTICS CORP. (US) | 1996-07-23 | — | — | US | disclosed |
| US-5241070-A | Biological analysis | CIBA CORNING DIAGNOSTICS CORP. (US) | 1993-08-31 | — | — | US | disclosed |
| EP-0361817-A2 | Nucleophilic polysubstituted aryl acridinium esters, conjugates, production and uses thereof | Ciba Corning Diagnostics Corp. (US) | 1990-04-04 | — | — | EP | disclosed |