Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 5/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991166 | 0.82 | ALDH1A1 (0.46) | ALDH1A1GLAHPGDKMT2AKDM4E | |
| Bromide SCHEMBL8000115 | 0.81 | ALDH1A1 (0.45) | ALDH1A1GLAHPGDKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL8519725 | 0.81 | ALDH1A1 (0.45) | ALDH1A1GLAHPGDKMT2AKDM4E | |
| SCHEMBL8003446 | 0.81 | KDM1A (0.45) | ALDH1A1GLAHPGDKMT2AKDM4E | |
| SCHEMBL9011359 | 0.80 | TRPV1 (0.42) | CYP1A2CYP2D6 | |
| SCHEMBL2872359 | 0.80 | KDM4E (0.55) | ALDH1A1GLAHPGDKMT2AKDM4E | |
| SCHEMBL28241450 | 0.79 | ESR1 (0.53) | ALDH1A1GLAHPGDKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL8003436 | 0.78 | ALDH1A1 (0.53) | ALDH1A1GLAHPGDKMT2AKDM4E | |
| Bromide SCHEMBL8003449 | 0.78 | KDM4E (0.53) | ALDH1A1GLAHPGDKMT2AKDM4E | |
| SCHEMBL5387138 | 0.78 | ALDH1A1 (0.52) | ALDH1A1GLAHPGDKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751951-A4 | DIAGNOSIS, THERAPY AND CELLULAR AND ANIMAL MODELS FOR DISEASES ASSOCIATED WITH MITOCHONDRIAL DEFECTS | MITOKOR (US) | 2000-05-03 | — | — | EP | disclosed |
| EP-0751951-A1 | DIAGNOSIS, THERAPY AND CELLULAR AND ANIMAL MODELS FOR DISEASES ASSOCIATED WITH MITOCHONDRIAL DEFECTS | Mitokor (US) | 1997-01-08 | — | — | EP | disclosed |