SCHEMBL8003544

SCHEMBL8003544

C=C(C)Oc1ccc(C(=O)O)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.63
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
KMT2A Q03164 1/20 0.52
ELANE P08246 2/20 0.51
TSHR P16473 3/20 0.50
TP53 P04637 2/20 0.50
POLB P06746 1/20 0.49
APEX1 P27695 1/20 0.49
HTT P42858 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
PARP15 Q460N3 1/20 0.47
PARP10 Q53GL7 1/20 0.47
ALDH1A1 P00352 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MAPK1 P28482 2/20 0.46
USP2 O75604 1/20 0.46
ALOX15 P16050 1/20 0.46
SRD5A2 P31213 2/20 0.46
PKM P14618 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL346685 0.84 ELANE (0.72) HSD17B10CA1CA2KMT2AELANE
SCHEMBL8840369 0.83 KDM4E (0.64) HSD17B10CA1CA2KMT2AELANE
SCHEMBL40184 0.83 HSD17B10 (0.88) HSD17B10CA1CA2KMT2AELANE
SCHEMBL11144108 0.82 LMNA (0.44) HSD17B10CA1CA2KMT2AELANE
SCHEMBL8840297 0.82 ELANE (0.46) HSD17B10KMT2AELANEALDH1A1SMN1; SMN2
SCHEMBL20442091 0.82 PARP10 (0.59) CA1CA2KMT2AELANEPARP15
SCHEMBL7026750 0.81 HSD17B10 (0.85) HSD17B10CA1CA2KMT2AELANE
Hydrochloric Acid SCHEMBL1374059 0.81 HSD17B10 (0.85) HSD17B10CA1CA2KMT2AELANE
Methane SCHEMBL7956977 0.81 HSD17B10 (0.85) HSD17B10CA1CA2KMT2AELANE
SCHEMBL19133742 0.80 HSD17B10 (0.69) HSD17B10CA1CA2KMT2AELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6057008-A PARTIAL POLYMERIZATION BY EXPOSURE TO ACTINIC LIGHT, DEFINED WAITING TIME WITHOUT EXPOSURE (DARK PHASE) AT A DEFINED TEMPERATURE, FIXING, POLYSILOXANE-BASED OLIGOMERS WHICH CONTAIN CHOLESTEROL DERIVATIVES CONSORTIUM FUR ELEKROCHEMISCHE INDUSTRIE GMBH (DE) 2000-05-02 US disclosed
US-5695680-A Liquid crystalline doristerol-containing organosiloxanes CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1997-12-09 US disclosed
US-5682212-A DISPLAY DEVICE CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1997-10-28 US disclosed
US-5098978-A LIQUID-CRYSTALLINE POLYMERS CONTAINING CHROMOPHORIC SIDE GROUPS CONSORTIUM FUR ELEKTROCHEMISCH IND. GMBH (DE) 1992-03-24 US disclosed
US-4410570-A CYCLIC ORGANOPOLYSILOXANE CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1983-10-18 US disclosed