Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 16/20 | 0.78 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.70 |
| ▸ | GC | P02774 | 1/20 | 0.70 |
| ▸ | PGR | P06401 | 1/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.70 |
| ▸ | RXRA | P19793 | 1/20 | 0.70 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.70 |
| ▸ | CNR1 | P21554 | 1/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.70 |
| ▸ | HTR2C | P28335 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.70 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.70 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.70 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6364731 | 1.00 | VDR (0.78) | VDRMAPTSMN1; SMN2NR1I2ABCB11 | |
| SCHEMBL8003696 | 1.00 | VDR (0.78) | VDRMAPTSMN1; SMN2NR1I2ABCB11 | |
| SCHEMBL6259692 | 1.00 | VDR (0.78) | VDRMAPTSMN1; SMN2NR1I2ABCB11 | |
| SCHEMBL3161619 | 0.98 | VDR (0.77) | VDRMAPTSMN1; SMN2NR1I2ABCB11 | |
| SCHEMBL8019534 | 0.98 | VDR (0.77) | VDRMAPTSMN1; SMN2NR1I2ABCB11 | |
| SCHEMBL8019537 | 0.98 | VDR (0.77) | VDRMAPTSMN1; SMN2NR1I2ABCB11 | |
| SCHEMBL14278413 | 0.98 | VDR (0.77) | VDRMAPTSMN1; SMN2NR1I2ABCB11 | |
| SCHEMBL6365594 | 0.98 | VDR (0.77) | VDRMAPTSMN1; SMN2NR1I2ABCB11 | |
| SCHEMBL8012877 | 0.97 | VDR (0.76) | VDRMAPTSMN1; SMN2NR1I2ABCB11 | |
| SCHEMBL8003748 | 0.97 | VDR (0.76) | VDRMAPTSMN1; SMN2NR1I2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877168-A | Vitamin D derivative with substituent at the 2β-position | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1999-03-02 | — | — | US | claimed |
| US-6124276-A | Vitamin D derivative with substituent at the 2β-position | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2000-09-26 | — | — | US | disclosed |
| US-5877168-A | Vitamin D derivative with substituent at the 2β-position | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1999-03-02 | — | — | US | disclosed |