Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 4/20 | 0.46 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5318283 | 0.86 | KDM4E (0.49) | HTR4HTR3AHTR1AADRA2CACHE | |
| SCHEMBL505934 | 0.83 | HTR4 (0.49) | HTR4HTR3AHTR1AADRA2CACHE | |
| SCHEMBL505936 | 0.83 | HTR4 (0.49) | HTR4HTR3AHTR1AADRA2CACHE | |
| SCHEMBL24001298 | 0.81 | HTR4 (0.65) | HTR4HTR3AHTR1AADRA2CACHE | |
| SCHEMBL3402337 | 0.81 | HTR4 (0.46) | HTR4HTR3AHTR1AADRA2CACHE | |
| SCHEMBL3408647 | 0.81 | HTR4 (0.46) | HTR4HTR3AHTR1AADRA2CACHE | |
| SCHEMBL1502009 | 0.81 | HTR4 (0.46) | HTR4HTR3AHTR1AADRA2CACHE | |
| SCHEMBL28891389 | 0.80 | HTR4 (0.50) | HTR4HTR3AHTR1AADRA2CACHE | |
| SCHEMBL19888414 | 0.79 | HTR4 (0.48) | HTR4HTR3AHTR1AADRA2CACHE | |
| SCHEMBL8508373 | 0.77 | HTR4 (0.46) | HTR4HTR3AHTR1AADRA2CACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009104729-A1 | AMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | 大日本住友製薬株式会社 (JP) | 2009-08-27 | — | — | WO | disclosed |