Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.38 |
| ▸ | RORA | P35398 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581271 | 0.89 | ALDH1A1 (0.48) | KDM4EMAPTALDH1A1HPGDHTT | |
| SCHEMBL8004925 | 0.89 | ALDH1A1 (0.48) | KDM4EMAPTALDH1A1HPGDHTT | |
| SCHEMBL7999652 | 0.85 | KDM4E (0.44) | KDM4EMAPTALDH1A1HPGDLMNA | |
| SCHEMBL8001735 | 0.85 | KDM4E (0.44) | KDM4EMAPTALDH1A1HPGDLMNA | |
| SCHEMBL7998533 | 0.83 | KDM4E (0.46) | KDM4EMAPTALDH1A1HPGDLMNA | |
| SCHEMBL7989113 | 0.83 | ALDH1A1 (0.47) | KDM4EMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7997334 | 0.83 | KDM4E (0.46) | KDM4EMAPTALDH1A1HPGDLMNA | |
| SCHEMBL7999961 | 0.83 | KDM4E (0.46) | KDM4EMAPTALDH1A1HPGDLMNA | |
| SCHEMBL7998893 | 0.83 | KDM4E (0.46) | KDM4EMAPTALDH1A1HPGDLMNA | |
| SCHEMBL7997085 | 0.82 | ALDH1A1 (0.43) | KDM4EMAPTALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1158265-C | Quinoline ketone derivant and antianaphylaction using same as active substance | ���ձ���ī��ѧ��ҵ��ʽ���� | 2004-07-21 | — | — | CN | disclosed |
| CN-1095834-C | Quinolinone derivatives and antiallergic agent containing said quinolinone derivatives as active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2002-12-11 | — | — | CN | disclosed |
| CN-1275564-A | Quinoline ketone derivant and antianaphylaction using same as active substance | DAINIPPON INK & CHEMICALS (JP) | 2000-12-06 | — | — | CN | disclosed |
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| CN-1163268-A | Quinolinone derivatives and antiallergic agent containing said quinolinone derivatives as active ingredient | LAINIPPON INK AND CHEMICALC IN (JP) | 1997-10-29 | — | — | CN | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |