SCHEMBL8004150

SCHEMBL8004150

CCCCCCCCOc1c(OC)c2ccc(NC(=O)/C=C/c3ccc(O)c(OC)c3)cc2n(CCCCCC)c1=O

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 11/20 0.49
BCHE P06276 6/20 0.45
ACHE P22303 6/20 0.45
TRPV1 Q8NER1 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7988377 1.00 KDM1A (0.49) KDM1ABCHEACHETRPV1
SCHEMBL8000936 0.94 KDM1A (0.49) KDM1ABCHEACHETRPV1
SCHEMBL8076802 0.94 KDM1A (0.49) KDM1ABCHEACHETRPV1
SCHEMBL7997822 0.92 KDM1A (0.51) KDM1ABCHEACHETRPV1
SCHEMBL7997820 0.92 KDM1A (0.51) KDM1ABCHEACHETRPV1
SCHEMBL8000910 0.87 BCHE (0.43) BCHEACHE
SCHEMBL8000909 0.87 BCHE (0.43) BCHEACHE
SCHEMBL8001689 0.86 KDM1A (0.51) KDM1ABCHEACHETRPV1
SCHEMBL8001693 0.86 KDM1A (0.51) KDM1ABCHEACHETRPV1
SCHEMBL8001387 0.84 L3MBTL1 (0.46) BCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6114352-A Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-09-05 US disclosed
EP-0785190-B1 Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient DAINIPPON INK & CHEMICALS (JP) 2000-08-16 EP disclosed
US-5942521-A Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient DAINIPPON INK AND CHEMICALS, INC. (JP) 1999-08-24 US disclosed
EP-0785190-A2 Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient DAINIPPON INK AND CHEMICALS, INC. (JP) 1997-07-23 EP disclosed