Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3915946 | 0.85 | CA2 (0.33) | CA2CA1CA9THRBLMNA | |
| SCHEMBL3920065 | 0.85 | CA2 (0.33) | CA2CA1CA9THRBLMNA | |
| SCHEMBL3927503 | 0.85 | CA2 (0.33) | CA2CA1CA9THRBLMNA | |
| SCHEMBL3921039 | 0.85 | CA2 (0.33) | CA2CA1CA9THRBLMNA | |
| SCHEMBL3917523 | 0.85 | CA2 (0.33) | CA2CA1CA9THRBLMNA | |
| SCHEMBL3920547 | 0.85 | CA2 (0.33) | CA2CA1CA9THRBLMNA | |
| SCHEMBL3922565 | 0.85 | CA2 (0.33) | CA2CA1CA9THRBLMNA | |
| SCHEMBL3929478 | 0.85 | CA2 (0.33) | CA2CA1CA9THRBLMNA | |
| SCHEMBL3917735 | 0.85 | CA2 (0.33) | CA2CA1CA9THRBLMNA | |
| SCHEMBL20367413 | 0.84 | CA2 (0.38) | CA2CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6077952-A | Cephaloporins and homologues | PFIZER INC. (US) | 2000-06-20 | — | — | US | disclosed |
| US-6020329-A | Cephaloporins and homologues, preparations and pharmaceutical compositions | PZIFER INC. (US) | 2000-02-01 | — | — | US | disclosed |
| EP-0540609-A1 | CEPHALOSPORINS AND HOMOLOGUES, PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS | PFIZER INC. (US) | 1993-05-12 | — | — | EP | disclosed |
| WO-1992001696-A1 | CEPHALOSPORINS AND HOMOLOGUES, PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS | BEECHAM GROUP PLC (GB) | 1992-02-06 | — | — | WO | disclosed |