Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 4/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 6/20 | 0.44 |
| ▸ | MMP2 | P08253 | 6/20 | 0.44 |
| ▸ | MMP9 | P14780 | 6/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 2/20 | 0.43 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8004484 | 1.00 | L3MBTL1 (0.49) | L3MBTL1EGFRSAE1UBA2RAB9A | |
| SCHEMBL8001168 | 0.93 | L3MBTL1 (0.49) | L3MBTL1EGFRSAE1UBA2RAB9A | |
| SCHEMBL8001165 | 0.93 | L3MBTL1 (0.49) | L3MBTL1EGFRSAE1UBA2RAB9A | |
| SCHEMBL7999359 | 0.90 | EGFR (0.48) | L3MBTL1EGFRSAE1UBA2RAB9A | |
| SCHEMBL7999362 | 0.90 | EGFR (0.48) | L3MBTL1EGFRSAE1UBA2RAB9A | |
| SCHEMBL7998861 | 0.90 | EGFR (0.48) | L3MBTL1EGFRSAE1UBA2RAB9A | |
| SCHEMBL7998864 | 0.90 | EGFR (0.48) | L3MBTL1EGFRSAE1UBA2RAB9A | |
| SCHEMBL8000616 | 0.90 | L3MBTL1 (0.47) | L3MBTL1EGFRSAE1UBA2RAB9A | |
| SCHEMBL8000619 | 0.90 | L3MBTL1 (0.47) | L3MBTL1EGFRSAE1UBA2RAB9A | |
| SCHEMBL7997514 | 0.89 | L3MBTL1 (0.47) | L3MBTL1EGFRSAE1UBA2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |