Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL330530 | 0.88 | ALDH1A1 (0.55) | ALDH1A1MAPTMEN1THRBKMT2A | |
| SCHEMBL12312330 | 0.88 | ALDH1A1 (0.68) | ALDH1A1MAPTMEN1THRBKMT2A | |
| Hydrochloric Acid SCHEMBL1143402 | 0.87 | ALDH1A1 (0.55) | ALDH1A1MAPTMEN1THRBKMT2A | |
| SCHEMBL3793239 | 0.87 | ALDH1A1 (0.57) | ALDH1A1MAPTMEN1THRBKMT2A | |
| Biphenyl SCHEMBL16950123 | 0.83 | TDP1 (0.73) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL25135225 | 0.82 | NCOA1 (0.57) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| Aniline SCHEMBL22169118 | 0.82 | ALDH1A1 (0.75) | ALDH1A1MAPTMEN1THRBKMT2A | |
| SCHEMBL30839809 | 0.79 | ALDH1A1 (0.67) | ALDH1A1MAPTMEN1THRBKMT2A | |
| SCHEMBL31607677 | 0.79 | ALDH1A1 (0.67) | ALDH1A1MAPTMEN1THRBKMT2A | |
| SCHEMBL6863931 | 0.79 | ALDH1A1 (0.67) | ALDH1A1MAPTMEN1THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000027394-A1 | ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | UNIVERSITY COLLEGE LONDON (GB) | 2000-05-18 | — | — | WO | disclosed |