SCHEMBL8004977

SCHEMBL8004977

CC(=O)Cc1ccccc1CO.COc1cccc(CC(=O)c2ccccc2)c1OC

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.46
MEN1 O00255 6/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 1/20 0.46
L3MBTL1 Q9Y468 4/20 0.46
HIF1A Q16665 1/20 0.46
ATM Q13315 1/20 0.45
POLB P06746 1/20 0.42
HTT P42858 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alcohol SCHEMBL28271101 0.88 L3MBTL1 (0.53) KMT2AMEN1NPC1RAB9AL3MBTL1
SCHEMBL265603 0.88 L3MBTL1 (0.56) KMT2AMEN1NPC1RAB9AL3MBTL1
Benzophenone SCHEMBL28093024 0.84 L3MBTL1 (0.56) KMT2AMEN1NPC1RAB9AL3MBTL1
Formic Acid SCHEMBL29290938 0.83 KMT2A (0.51) KMT2AMEN1NPC1RAB9AL3MBTL1
SCHEMBL2586902 0.83 CYP3A4 (0.53) KMT2AMEN1L3MBTL1HIF1AATM
SCHEMBL18039270 0.81 KMT2A (0.46) KMT2AMEN1NPC1RAB9AL3MBTL1
SCHEMBL8004983 0.80 KMT2A (0.44) KMT2AMEN1NPC1RAB9AL3MBTL1
SCHEMBL10078464 0.80 KMT2A (0.48) KMT2AMEN1NPC1RAB9AL3MBTL1
SCHEMBL28329504 0.78 NPC1 (0.51) KMT2AMEN1NPC1RAB9AL3MBTL1
SCHEMBL28124286 0.77 KDM4E (0.55) KMT2AMEN1NPC1RAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0895606-A4 COATED OPTICAL FIBERS HAVING A REDUCED CONTENT OF EXTRACTABLE AND VOLATILE MATERIAL BORDEN CHEM INC (US) 2000-12-06 EP disclosed
EP-0895606-A1 COATED OPTICAL FIBERS HAVING A REDUCED CONTENT OF EXTRACTABLE AND VOLATILE MATERIAL BORDEN CHEMICAL, INC. (US) 1999-02-10 EP disclosed
WO-1998019189-A1 COATED OPTICAL FIBERS HAVING A REDUCED CONTENT OF EXTRACTABLE AND VOLATILE MATERIAL BORDEN CHEMICAL, INC. (US) 1998-05-07 WO disclosed
US-5744514-A PROTECTIVE COATING COMPRISING A RADIATION-CURED MERCAPTO-TERMINATED URETHANE OLIGOMER, A (METH)ACRYLATED POLYURETHANE AND AN ACRYLATE DILUENT; HEAT AND SOLVENT RESISTANCE; HIGH TENSILE MODULUS BORDEN CHEMICAL, INC. (US) 1998-04-28 US disclosed