SCHEMBL8005250

SCHEMBL8005250

CSC(C)c1ccc(C(=O)c2ccc(Cl)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.50
SRD5A2 P31213 1/20 0.50
HPGD P15428 2/20 0.49
CNR1 P21554 2/20 0.45
CNR2 P34972 1/20 0.45
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
PPARG P37231 2/20 0.43
PPARA Q07869 2/20 0.43
TSHR P16473 2/20 0.43
LMNA P02545 2/20 0.43
USP2 O75604 1/20 0.43
ABCB11 O95342 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
MAPT P10636 1/20 0.43
CYP2C9 P11712 1/20 0.43
ADRB3 P13945 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1145645 0.84 ADRB2 (0.52) MAPK1HPGDTSHRLMNASLC6A2
SCHEMBL3151943 0.83 CNR1 (0.60) MAPK1SRD5A2HPGDCNR1CNR2
SCHEMBL8007548 0.82 MEN1 (0.49) MAPK1HPGDMEN1KMT2ASMN1; SMN2
SCHEMBL18681398 0.79 ADRB2 (0.46) MAPK1HPGDTSHRLMNACYP1A2
SCHEMBL8010830 0.78 SRD5A2 (0.46) MAPK1SRD5A2HPGDCNR1CNR2
SCHEMBL8008483 0.78 MAPK1 (0.53) MAPK1SRD5A2HPGDCNR1CNR2
SCHEMBL11993889 0.78 MAPK1 (0.53) MAPK1SRD5A2HPGDCNR1CNR2
SCHEMBL734544 0.77 HPGD (0.48) MAPK1HPGDKMT2ASMN1; SMN2LMNA
SCHEMBL8004406 0.76 SRD5A2 (0.43) MAPK1SRD5A2HPGDCNR1CNR2
SCHEMBL9065412 0.76 SRD5A2 (0.80) MAPK1SRD5A2HPGDCNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6077866-A EXHIBIT POWERFUL INSECTICIDAL ACTION, ESPECIALLY AGAINST LEPIDOPTERA, COLEOPTERA AND SOIL INSECTS NIHON BAYER AGROCHEM K.K. (JP) 2000-06-20 US disclosed
EP-0742202-B1 Benzophenone hydrazone derivatives as insecticides BAYER AGROCHEM KK (JP) 1999-12-01 EP disclosed
EP-0742202-A2 Benzophenone hydrazone derivatives as insecticides NIHON BAYER AGROCHEM K.K. (JP) 1996-11-13 EP disclosed