Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11562772 | 0.90 | OPRM1 (0.54) | OPRM1SLC22A1ABCB1CA12CA1 | |
| SCHEMBL16440623 | 0.89 | CA12 (0.61) | OPRM1SLC22A1ABCB1CA12CA1 | |
| SCHEMBL11568939 | 0.87 | OPRM1 (0.54) | OPRM1SLC22A1ABCB1CA12CA1 | |
| SCHEMBL801021 | 0.85 | OPRM1 (0.55) | OPRM1SLC22A1ABCB1CA12CA1 | |
| SCHEMBL9152974 | 0.83 | CA12 (0.61) | OPRM1CA12CA1CA2CA4 | |
| SCHEMBL800612 | 0.80 | OPRM1 (0.48) | OPRM1SLC22A1ABCB1OPRD1 | |
| SCHEMBL780308 | 0.80 | NPFFR1 (0.49) | OPRM1SLC22A1ABCB1CA12CA1 | |
| Alcohol SCHEMBL7851452 | 0.80 | OPRM1 (0.48) | OPRM1SLC22A1ABCB1OPRD1TSHR | |
| SCHEMBL13490813 | 0.79 | CACNA1C (0.51) | OPRM1CA12CA1CA2CA4 | |
| SCHEMBL11566308 | 0.78 | CA12 (0.47) | OPRM1CA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946433-B2 | Process for the preparation of sufentanil base and related compounds | MALLINCKRODT LLC (US) | 2015-02-03 | — | — | US | disclosed |
| US-20120071659-A1 | Process for the Preparation of Sufentanil Base and Related Compounds | MALLINCKRODT LLC (US) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071659-A1 | Process for the Preparation of Sufentanil Base and Related Compounds | SNRPD1, SNRPD2, SNRPA1 | OPRM1 18/4885SLC22A1 2445/4885ABCB1 1242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.