Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 14/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12106068 | 0.85 | FAAH (0.58) | FAAHKCNH2PTGS2PTGS1 | |
| SCHEMBL12106019 | 0.81 | FAAH (0.62) | FAAHKCNH2PTGS2PTGS1 | |
| SCHEMBL1303953 | 0.81 | FAAH (0.55) | FAAHKCNH2PTGS2PTGS1 | |
| SCHEMBL8005584 | 0.81 | FAAH (0.52) | FAAHKCNH2PTGS2PTGS1 | |
| SCHEMBL1304370 | 0.80 | FAAH (0.53) | FAAHKCNH2PTGS2PTGS1 | |
| SCHEMBL1302731 | 0.80 | FAAH (0.53) | FAAHKCNH2PTGS2PTGS1 | |
| SCHEMBL8004024 | 0.78 | FAAH (0.54) | FAAHKCNH2PTGS2PTGS1 | |
| SCHEMBL12106262 | 0.78 | FAAH (0.58) | FAAHKCNH2PTGS2PTGS1 | |
| SCHEMBL1303082 | 0.78 | FAAH (0.54) | FAAHKCNH2PTGS2PTGS1 | |
| SCHEMBL12106327 | 0.77 | FAAH (0.79) | FAAHKCNH2PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009152025-A1 | IMIDAZOLE DERIVATIVES USEFUL AS INHIBITORS OF FAAH | MERCK & CO., INC. (US) | 2009-12-17 | — | — | WO | disclosed |