Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8005920 | 1.00 | DPP4 (0.35) | DPP4DPP8DPP9DPP7GPR88 | |
| SCHEMBL9008551 | 1.00 | DPP4 (0.35) | DPP4DPP8DPP9DPP7GPR88 | |
| SCHEMBL8005913 | 1.00 | DPP4 (0.35) | DPP4DPP8DPP9DPP7GPR88 | |
| SCHEMBL8415942 | 0.91 | GRIA4 (0.34) | ESR2CYP2C9 | |
| SCHEMBL8415944 | 0.91 | GRIA4 (0.34) | ESR2CYP2C9 | |
| SCHEMBL7758900 | 0.91 | APP (0.33) | DPP4DPP8DPP9DPP7GPR88 | |
| SCHEMBL7758905 | 0.91 | APP (0.33) | DPP4DPP8DPP9DPP7GPR88 | |
| SCHEMBL7758004 | 0.84 | CYP2C9 (0.35) | ESR2CYP2C9 | |
| SCHEMBL7758012 | 0.84 | CYP2C9 (0.35) | ESR2CYP2C9 | |
| SCHEMBL8022480 | 0.84 | CYP2C9 (0.35) | ESR2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670322-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 2000-01-19 | — | — | EP | disclosed |
| US-5582764-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| EP-0670322-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-09-06 | — | — | EP | disclosed |