Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415942 | 1.00 | GRIA4 (0.34) | GRIA4USP30HCRTR2ESR2OPRL1 | |
| SCHEMBL9008551 | 0.91 | DPP4 (0.35) | ESR2CYP2C9 | |
| SCHEMBL8005915 | 0.91 | DPP4 (0.35) | ESR2CYP2C9 | |
| SCHEMBL8005913 | 0.91 | DPP4 (0.35) | ESR2CYP2C9 | |
| SCHEMBL8005920 | 0.91 | DPP4 (0.35) | ESR2CYP2C9 | |
| SCHEMBL8398773 | 0.88 | GRIA4 (0.35) | GRIA4USP30HCRTR2HTR2AHTR2C | |
| SCHEMBL8398767 | 0.88 | GRIA4 (0.35) | GRIA4USP30HCRTR2HTR2AHTR2C | |
| SCHEMBL8040030 | 0.88 | GRIA4 (0.35) | GRIA4USP30HCRTR2HTR2AHTR2C | |
| SCHEMBL8040028 | 0.88 | GRIA4 (0.35) | GRIA4USP30HCRTR2HTR2AHTR2C | |
| SCHEMBL8415915 | 0.87 | GRIA4 (0.32) | GRIA4USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648773-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-09-08 | — | — | EP | disclosed |
| US-5547606-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-20 | — | — | US | disclosed |
| EP-0648773-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-04-19 | — | — | EP | disclosed |