Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 17/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2823790 | 0.82 | GRM2 (0.84) | GRM2 | |
| SCHEMBL7996030 | 0.77 | GRM2 (0.43) | GRM2 | |
| SCHEMBL7996006 | 0.76 | GRM2 (0.42) | GRM2 | |
| SCHEMBL8008771 | 0.74 | GRM2 (0.53) | GRM2MAPK1L3MBTL1 | |
| SCHEMBL2823952 | 0.73 | GRM2 (1.00) | GRM2 | |
| SCHEMBL8008592 | 0.71 | GRM2 (0.42) | GRM2 | |
| SCHEMBL8007853 | 0.71 | GRM2 (0.38) | GRM2POLB | |
| SCHEMBL13251414 | 0.70 | ALDH1A1 (0.68) | GRM2KMT2A | |
| SCHEMBL2825762 | 0.70 | GRM2 (0.83) | GRM2 | |
| SCHEMBL29728149 | 0.68 | GRM2 (0.38) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009094265-A1 | 3,5-SUBSTITUTED-1,3-OXAZOLIDIN-2-ONE DERIVATIVES | MERCK & CO., INC. (US) | 2009-07-30 | — | — | WO | disclosed |