Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ5 | P48544 | 3/20 | 0.55 |
| ▸ | KCNJ3 | P48549 | 3/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024028 | 0.87 | AR (0.57) | KCNJ5KCNJ3ARALDH1A1MEN1 | |
| SCHEMBL8006346 | 0.84 | AR (0.47) | KCNJ5KCNJ3ARALDH1A1MEN1 | |
| SCHEMBL14295894 | 0.82 | AR (0.49) | KCNJ5KCNJ3ARTRPV1ALDH1A1 | |
| SCHEMBL14300662 | 0.80 | AR (0.47) | ARTRPV1 | |
| SCHEMBL14300661 | 0.76 | AR (0.41) | KCNJ5KCNJ3ARALDH1A1MEN1 | |
| SCHEMBL2031406 | 0.75 | AR (0.71) | ARMAPTKDRCYP3A4CNR2 | |
| SCHEMBL8021006 | 0.75 | AR (0.48) | ARMEN1LMNAMAPTKMT2A | |
| SCHEMBL8024928 | 0.74 | AR (0.48) | ARKDR | |
| SCHEMBL12584028 | 0.72 | AR (0.56) | AR | |
| SCHEMBL14295896 | 0.71 | MEN1 (0.39) | KCNJ5KCNJ3ARMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097995-A1 | NOVEL PHENYL-SUBSTITUTED IMIDAZOLIDINES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS AND USE THEREOF | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | WO | disclosed |