Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8015251 | 0.80 | AR (0.46) | ARKDRCDK8 | |
| SCHEMBL8005353 | 0.78 | CNR1 (0.46) | AR | |
| SCHEMBL8018561 | 0.78 | AR (0.47) | ARGRM4CDK8 | |
| SCHEMBL8021637 | 0.77 | RORC (0.40) | AR | |
| SCHEMBL13745415 | 0.77 | AR (0.44) | AR | |
| SCHEMBL8005970 | 0.74 | KCNJ5 (0.55) | ARKDR | |
| SCHEMBL8024028 | 0.74 | AR (0.57) | ARS1PR1 | |
| SCHEMBL14295100 | 0.74 | NTRK1 (0.44) | AR | |
| SCHEMBL13746288 | 0.74 | MAPK14 (0.38) | ARKDR | |
| SCHEMBL8029788 | 0.74 | AR (0.60) | ARGRM4S1PR1KDRCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097995-A1 | NOVEL PHENYL-SUBSTITUTED IMIDAZOLIDINES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS AND USE THEREOF | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | WO | disclosed |