Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11669536 | 0.82 | NPSR1 (0.48) | TRPM8NPSR1ALDH1A1POLBKMT2A | |
| SCHEMBL18426946 | 0.80 | NPSR1 (0.42) | TRPM8NPSR1ALDH1A1POLBKMT2A | |
| SCHEMBL1629579 | 0.79 | TRPM8 (0.57) | TRPM8NPSR1ALDH1A1POLBKMT2A | |
| SCHEMBL11399712 | 0.77 | KMT2A (0.47) | NPSR1ALDH1A1POLBKMT2ANPC1 | |
| SCHEMBL5580475 | 0.77 | NPSR1 (0.43) | TRPM8NPSR1ALDH1A1POLBKMT2A | |
| SCHEMBL30764040 | 0.77 | TRPM8 (0.66) | TRPM8NPSR1ALDH1A1POLBKMT2A | |
| SCHEMBL13806253 | 0.76 | TRPM8 (0.53) | TRPM8NPSR1ALDH1A1POLBKMT2A | |
| SCHEMBL9456609 | 0.75 | NPSR1 (0.64) | TRPM8NPSR1ALDH1A1POLBKMT2A | |
| SCHEMBL10271031 | 0.74 | TRPM8 (1.00) | TRPM8NPSR1ALDH1A1NPC1TDP1 | |
| SCHEMBL30532219 | 0.74 | TRPM8 (1.00) | TRPM8NPSR1ALDH1A1NPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081974-B1 | POLYCARBONATES AND COPOLYCARBONATES WITH IMPROVED METAL ADHESION | BAYER MATERIALSCIENCE AG (DE) | 2011-02-23 | — | — | EP | disclosed |
| US-7547755-B2 | (Co)polycarbonates having improved adhesion to metals | BAYER MATERIAL SCIENCE AG (DE) | 2009-06-16 | — | — | US | disclosed |
| US-7547755-B2 | (Co)polycarbonates having improved adhesion to metals | BAYER MATERIAL SCIENCE AG (DE) | 2009-06-16 | — | — | US | disclosed |
| WO-2008037364-A1 | POLYCARBONATES AND COPOLYCARBONATES WITH IMPROVED METAL ADHESION | BAYER MATERIALSCIENCE AG (DE) | 2008-04-03 | — | — | WO | disclosed |
| US-20080081896-A1 | (Co)polycarbonates having improved adhesion to metals | COVESTRO DEUTSCHLAND AG (DE) | 2008-04-03 | — | — | US | disclosed |
| US-20080081896-A1 | (Co)polycarbonates having improved adhesion to metals | COVESTRO DEUTSCHLAND AG (DE) | 2008-04-03 | — | — | US | disclosed |
| EP-0944636-A4 | PHENYL GLYOXAMIDES AS sPLA2 INHIBITORS | LILLY CO ELI (US) | 2000-07-12 | — | — | EP | disclosed |
| EP-0944636-A1 | PHENYL GLYOXAMIDES AS sPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998024794-A1 | PHENYL GLYOXAMIDES AS sPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 1998-06-11 | — | — | WO | disclosed |