Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 9/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 9/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 9/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 9/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17817181 | 1.00 | POLB (0.64) | POLBKMT2AMEN1LMNAGAA | |
| SCHEMBL14434181 | 0.86 | POLB (0.61) | POLBKMT2AMEN1LMNAGAA | |
| SCHEMBL8909239 | 0.83 | HTR1A (0.85) | LMNASMN1; SMN2HTR1AADRA1DADRA1A | |
| SCHEMBL31197375 | 0.83 | HTR1A (0.85) | LMNASMN1; SMN2HTR1AADRA1DADRA1A | |
| SCHEMBL15923360 | 0.83 | HTR1A (0.85) | LMNASMN1; SMN2HTR1AADRA1DADRA1A | |
| SCHEMBL9652157 | 0.83 | HTR1A (0.85) | LMNASMN1; SMN2HTR1AADRA1DADRA1A | |
| SCHEMBL31197364 | 0.83 | HTR1A (0.85) | LMNASMN1; SMN2HTR1AADRA1DADRA1A | |
| SCHEMBL16916968 | 0.81 | HTR1A (0.82) | LMNASMN1; SMN2HTR1AADRA1DADRA1A | |
| SCHEMBL30307405 | 0.81 | HTR1A (0.82) | LMNASMN1; SMN2HTR1AADRA1DADRA1A | |
| SCHEMBL27512057 | 0.80 | TLR8 (0.58) | LMNAGAAMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000024389-A2 | BENZOQUINOLINE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | ANADYS PHARMACEUTICALS, INC. (US) | 2000-05-04 | — | — | WO | disclosed |