Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 4/20 | 0.82 |
| ▸ | CTSB | P07858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HNF4A | P41235 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30878647 | 0.91 | HPRT1 (1.00) | HPRT1CTSBALDH1A1TDP1TSHR | |
| SCHEMBL710252 | 0.91 | HPRT1 (1.00) | HPRT1CTSBALDH1A1TDP1TSHR | |
| SCHEMBL29450700 | 0.91 | HPRT1 (1.00) | HPRT1CTSBALDH1A1TDP1TSHR | |
| Charcoal, Activated SCHEMBL5052441 | 0.89 | HPRT1 (0.96) | HPRT1CTSBALDH1A1TDP1TSHR | |
| SCHEMBL30076625 | 0.82 | HPRT1 (1.00) | HPRT1ALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL93764 | 0.82 | HPRT1 (1.00) | HPRT1ALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL29804869 | 0.82 | HPRT1 (1.00) | HPRT1ALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL6245129 | 0.80 | HPRT1 (0.78) | HPRT1CTSBALDH1A1TDP1TSHR | |
| SCHEMBL1556587 | 0.79 | ALDH1A1 (0.78) | HPRT1CTSBALDH1A1TDP1TSHR | |
| SCHEMBL31677740 | 0.79 | ALDH1A1 (0.78) | HPRT1CTSBALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6015811-A | Antitumor Chrysene derivatives | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2000-01-18 | — | — | US | disclosed |