Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 18/20 | 0.53 |
| ▸ | FNTB | P49356 | 18/20 | 0.53 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.41 |
| ▸ | NRAS | P01111 | 1/20 | 0.41 |
| ▸ | HRAS | P01112 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3683094 | 1.00 | FNTA (0.53) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL3500218 | 1.00 | FNTA (0.53) | FNTAFNTBPGGT1BNRASHRAS | |
| Hydrochloric Acid SCHEMBL8591189 | 0.99 | FNTA (0.53) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL3685883 | 0.94 | FNTA (0.56) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL3684995 | 0.94 | FNTA (0.56) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL3501299 | 0.94 | FNTA (0.56) | FNTAFNTBPGGT1BNRASHRAS | |
| Hydrochloric Acid SCHEMBL9082057 | 0.94 | FNTA (0.55) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL3499936 | 0.90 | FNTA (0.49) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL3685047 | 0.90 | FNTA (0.49) | FNTAFNTBPGGT1BNRASHRAS | |
| Hydrochloric Acid SCHEMBL8544538 | 0.89 | FNTA (0.48) | FNTAFNTBPGGT1BNRASHRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000025789-A1 | A METHOD OF TREATING ENDOMETRIOSIS | MERCK & CO., INC. (US) | 2000-05-11 | — | — | WO | disclosed |
| EP-0820445-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1998-01-28 | — | — | EP | disclosed |