Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 18/20 | 0.56 |
| ▸ | FNTB | P49356 | 18/20 | 0.56 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.42 |
| ▸ | NRAS | P01111 | 1/20 | 0.42 |
| ▸ | HRAS | P01112 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3501299 | 1.00 | FNTA (0.56) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL3685883 | 1.00 | FNTA (0.56) | FNTAFNTBPGGT1BNRASHRAS | |
| Hydrochloric Acid SCHEMBL9082057 | 0.99 | FNTA (0.55) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL3683094 | 0.94 | FNTA (0.53) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL8006493 | 0.94 | FNTA (0.53) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL3500218 | 0.94 | FNTA (0.53) | FNTAFNTBPGGT1BNRASHRAS | |
| Hydrochloric Acid SCHEMBL8591189 | 0.94 | FNTA (0.53) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL8034890 | 0.92 | FNTA (0.47) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL8154511 | 0.92 | FNTA (0.47) | FNTAFNTBPGGT1BNRASHRAS | |
| Hydrochloric Acid SCHEMBL8147142 | 0.91 | FNTA (0.46) | FNTAFNTBPGGT1BNRASHRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057028-A9 | TREATMENT OF PROTEINOPATHIES USING A FARNESYL TRANSFERASE INHIBITOR | LINK MEDICINE CORPORATION (US) | 2010-09-02 | — | — | WO | disclosed |
| WO-2010057028-A2 | TREATMENT OF PROTEINOPATHIES USING A FARNESYL TRANSFERASE INHIBITOR | LINK MEDICINE CORPORATION (US) | 2010-05-20 | — | — | WO | disclosed |
| EP-1744751-A2 | METHODS FOR THE TREATMENT OF SYNUCLEINOPATHIES | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005089502-A2 | METHODS FOR THE TREATMENT OF SYNUCLEINOPATHIES | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2005-09-29 | — | — | WO | disclosed |