Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 4/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL818934 | 1.00 | GABRR1 (0.46) | GABRR1ACEAKR1C3AKR1C1PLG | |
| SCHEMBL29156402 | 1.00 | GABRR1 (0.46) | GABRR1ACEAKR1C3AKR1C1PLG | |
| SCHEMBL14543168 | 0.85 | ACE (0.42) | GABRR1ACEAKR1C3AKR1C1PLG | |
| SCHEMBL6712870 | 0.85 | ACE (0.42) | GABRR1ACEAKR1C3AKR1C1PLG | |
| SCHEMBL9684009 | 0.85 | GABRR1 (0.46) | GABRR1ACEAKR1C3AKR1C1LMNA | |
| SCHEMBL20128072 | 0.83 | CHRNB2 (0.40) | AKR1C3AKR1C1BTK | |
| SCHEMBL601704 | 0.83 | GABRR1 (0.44) | GABRR1ACEAKR1C3AKR1C1PLG | |
| Hydrochloric Acid SCHEMBL11822183 | 0.83 | ACE (0.41) | GABRR1ACEAKR1C3AKR1C1PLG | |
| SCHEMBL20768494 | 0.82 | GABRR1 (0.35) | GABRR1ACEAKR1C3AKR1C1PLG | |
| SCHEMBL14186720 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107447-A | LIQUID CRYSTALLINE POLYMERS | HOECHST RESEARCH TECHNOLOGY DEUTCHLAND GMBH & CO. KG (DE) | 2000-08-22 | — | — | US | disclosed |