Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2896961 | 1.00 | CHRM1 (0.39) | CHRM1CHRM2CHRM3SLC6A2SLC6A4 | |
| SCHEMBL31618664 | 0.88 | CHRM2 (0.34) | CHRM1CHRM2CHRM3 | |
| SCHEMBL3943932 | 0.80 | — | — | |
| SCHEMBL24764448 | 0.77 | — | — | |
| SCHEMBL10290697 | 0.77 | — | — | |
| SCHEMBL9723824 | 0.77 | SLC2A1 (0.38) | — | |
| SCHEMBL2632683 | 0.76 | CHRM1 (0.51) | CHRM1CHRM2CHRM3SLC6A2SLC6A4 | |
| SCHEMBL24764219 | 0.76 | CHRM1 (0.38) | CHRM1CHRM2CHRM3SLC6A2SLC6A4 | |
| SCHEMBL10049922 | 0.76 | CHRM1 (0.51) | CHRM1CHRM2CHRM3SLC6A2SLC6A4 | |
| SCHEMBL24764467 | 0.76 | CHRM1 (0.38) | CHRM1CHRM2CHRM3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009108507-A1 | THERAPEUTIC COMPOUNDS | MERCK & CO., INC. (US) | 2009-09-03 | — | — | WO | disclosed |