Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31267671 | 0.83 | NPC1 (0.39) | SLC2A1LPAR3LPAR2PRKCA | |
| SCHEMBL31267589 | 0.81 | NPC1 (0.42) | SLC2A1LPAR3LPAR2PRKCA | |
| SCHEMBL3943006 | 0.77 | NPC1 (0.36) | SLC2A1LPAR3LPAR2 | |
| SCHEMBL4036898 | 0.77 | NPC1 (0.41) | SLC2A1LPAR3LPAR2PRKCA | |
| SCHEMBL8006752 | 0.77 | CHRM1 (0.39) | — | |
| SCHEMBL2896961 | 0.77 | CHRM1 (0.39) | — | |
| SCHEMBL31618664 | 0.76 | CHRM2 (0.34) | — | |
| SCHEMBL3946956 | 0.76 | NPC1 (0.44) | SLC2A1PRKCA | |
| SCHEMBL3933992 | 0.76 | NPC1 (0.44) | SLC2A1PRKCA | |
| SCHEMBL9723748 | 0.76 | LPAR2 (0.33) | SLC2A1LPAR3LPAR2PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368933-B1 | COMPOSITIONS COMPRISING 1-OXO- OR THIOHYDROCARBYL SUBSTITUTED AZACYCLOALKANES | Whitby Research Incorporated (US) | 1992-10-14 | — | — | EP | disclosed |
| EP-0368933-A1 | COMPOSITIONS COMPRISING 1-OXO- OR THIOHYDROCARBYL SUBSTITUTED AZACYCLOALKANES | Whitby Research Incorporated (US) | 1990-05-23 | — | — | EP | disclosed |