Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | METAP2 | P50579 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 11/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8492486 | 1.00 | SIGMAR1 (0.51) | SIGMAR1METAP2EPHX1EPHX2METAP1 | |
| SCHEMBL12829172 | 0.98 | SIGMAR1 (0.53) | SIGMAR1METAP2EPHX1EPHX2 | |
| SCHEMBL6876305 | 0.94 | METAP1 (0.49) | SIGMAR1METAP2EPHX1METAP1 | |
| SCHEMBL6876886 | 0.94 | METAP1 (0.49) | SIGMAR1METAP2EPHX1METAP1 | |
| SCHEMBL6875880 | 0.94 | METAP1 (0.49) | SIGMAR1METAP2EPHX1METAP1 | |
| SCHEMBL3411145 | 0.94 | METAP1 (0.49) | SIGMAR1METAP2EPHX1METAP1 | |
| Hydrochloric Acid SCHEMBL742741 | 0.92 | METAP1 (0.48) | SIGMAR1METAP2EPHX1METAP1 | |
| Hydrochloric Acid SCHEMBL742742 | 0.92 | METAP1 (0.48) | SIGMAR1METAP2EPHX1METAP1 | |
| SCHEMBL8491681 | 0.91 | SMN1; SMN2 (0.46) | SIGMAR1METAP2EPHX1EPHX2 | |
| SCHEMBL13338123 | 0.88 | SMN1; SMN2 (0.42) | SIGMAR1METAP2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1616859-B1 | Substituted cyclohexyl carboxylic acid compounds | SEIKAGAKU KOGYO CO LTD (JP) | 2013-09-04 | — | — | EP | disclosed |
| EP-1616859-B1 | Substituted cyclohexyl carboxylic acid compounds | SEIKAGAKU KOGYO CO LTD (JP) | 2013-09-04 | — | — | EP | disclosed |
| EP-1008592-B1 | Cyclic amide derivatives which inhibit cathepsin K | SEIKAGAKU KOGYO CO LTD (JP) | 2006-02-01 | — | — | EP | disclosed |
| US-6117870-A | USEFUL AS THERAPEUTIC DRUG OR PREVENTIVE DRUG OF ARTHRITIS AND RHEUMATISM DUE TO INCREASE OF BONE RESORPTION IN ADDITION TO BONE DISEASES SUCH AS OSTEOPOROSIS, HYPERCALCEMIA, AND PAGET'S DISEASE | FUJIREBIO KABUSHIKI KAISHA (JP) | 2000-09-12 | — | — | US | disclosed |