Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.52 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.52 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.45 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.45 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1133842 | 0.89 | LMNA (0.51) | LMNAGRIA1HDAC4HDAC3HDAC1 | |
| SCHEMBL210916 | 0.89 | LMNA (0.51) | LMNAGRIA1HDAC4HDAC3HDAC1 | |
| SCHEMBL2121460 | 0.89 | LMNA (0.51) | LMNAGRIA1HDAC4HDAC3HDAC1 | |
| SCHEMBL10336285 | 0.86 | LMNA (0.52) | LMNAGRIA1HDAC4HDAC3HDAC1 | |
| SCHEMBL10336284 | 0.86 | LMNA (0.52) | LMNAGRIA1HDAC4HDAC3HDAC1 | |
| SCHEMBL9828179 | 0.83 | LMNA (0.57) | LMNASCN9AHDAC1HDAC6CTSL | |
| SCHEMBL2228194 | 0.83 | LMNA (0.57) | LMNASCN9AHDAC1HDAC6CTSL | |
| SCHEMBL7415827 | 0.82 | GRIA1 (0.52) | LMNAGRIA1HDAC4HDAC3HDAC1 | |
| SCHEMBL27536574 | 0.82 | GRIA1 (0.52) | LMNAGRIA1HDAC4HDAC3HDAC1 | |
| SCHEMBL9002994 | 0.81 | ERAP2 (0.51) | ERAP2ERAP1LNPEPCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973801-A1 | GnRH ANTAGONISTS | FERRING B.V. (NL) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998046635-A1 | GnRH ANTAGONISTS | FERRING BV (NL) | 1998-10-22 | — | — | WO | disclosed |