Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8006995 | 1.00 | MAPT (0.34) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL13483655 | 0.88 | NPSR1 (0.34) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL5505218 | 0.87 | POLB (0.37) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL5505216 | 0.87 | POLB (0.37) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL7997970 | 0.86 | NPSR1 (0.34) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL7997968 | 0.86 | NPSR1 (0.34) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL9096745 | 0.85 | CYP2D6 (0.36) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL9096749 | 0.85 | CYP2D6 (0.36) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL9096741 | 0.85 | CYP2D6 (0.36) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL10366514 | 0.84 | NPSR1 (0.35) | MAPTMEN1KMT2ALMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593766-B1 | PYRIDONECARBOXYLIC ACID DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2000-09-06 | — | — | EP | disclosed |
| EP-0593766-A1 | PYRIDONECARBOXYLIC ACID DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |