Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997968 | 1.00 | NPSR1 (0.34) | NPSR1MAPTMEN1KMT2ACYP2D6 | |
| SCHEMBL9096741 | 0.94 | CYP2D6 (0.36) | NPSR1MAPTMEN1KMT2ACYP2D6 | |
| SCHEMBL9096745 | 0.94 | CYP2D6 (0.36) | NPSR1MAPTMEN1KMT2ACYP2D6 | |
| SCHEMBL9096749 | 0.94 | CYP2D6 (0.36) | NPSR1MAPTMEN1KMT2ACYP2D6 | |
| SCHEMBL8006995 | 0.86 | MAPT (0.34) | NPSR1MAPTMEN1KMT2ACYP2D6 | |
| SCHEMBL8006993 | 0.86 | MAPT (0.34) | NPSR1MAPTMEN1KMT2ACYP2D6 | |
| SCHEMBL13483599 | 0.85 | MAPT (0.36) | NPSR1MAPTMEN1KMT2ACYP2D6 | |
| SCHEMBL8111818 | 0.85 | TAS1R3 (0.36) | NPSR1MAPTMEN1KMT2ACYP2D6 | |
| SCHEMBL8111817 | 0.85 | TAS1R3 (0.36) | NPSR1MAPTMEN1KMT2ACYP2D6 | |
| SCHEMBL8111880 | 0.82 | CYP2D6 (0.45) | NPSR1MAPTMEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593766-B1 | PYRIDONECARBOXYLIC ACID DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2000-09-06 | — | — | EP | disclosed |
| US-5696132-A | MICROBIOCIDES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-12-09 | — | — | US | disclosed |
| EP-0593766-A1 | PYRIDONECARBOXYLIC ACID DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |