Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | DUT | P33316 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722932 | 0.88 | AOC3 (0.50) | KDM4EATMSLC6A4RIPK1MEN1 | |
| SCHEMBL20611086 | 0.88 | AOC3 (0.50) | KDM4EATMSLC6A4RIPK1MEN1 | |
| SCHEMBL23699426 | 0.86 | CYP2C19 (0.41) | TACR1KDM4EATMSLC6A4HTR2C | |
| SCHEMBL1529744 | 0.86 | AURKA (0.42) | KDM4EATMSLC6A4HTR2CCTSS | |
| SCHEMBL3661247 | 0.85 | CCR5 (0.41) | KDM4EATMSLC6A4HTR2CRIPK1 | |
| SCHEMBL23334606 | 0.85 | CCR5 (0.41) | KDM4EATMSLC6A4HTR2CRIPK1 | |
| SCHEMBL2067961 | 0.84 | HTR2A (0.43) | TACR1HTR2AHRH1TDP1ATM | |
| SCHEMBL14686241 | 0.84 | KDM4E (0.39) | TACR1KDM4EATMSLC6A4HTR2C | |
| SCHEMBL23699047 | 0.83 | MME (0.40) | KDM4EATMSLC6A4HTR2CCTSS | |
| SCHEMBL23699048 | 0.83 | MME (0.40) | KDM4EATMSLC6A4HTR2CCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060484-A | Anti-viral method | ELI LILLY AND COMPANY (US) | 2000-05-09 | — | — | US | disclosed |
| EP-0806205-A2 | Urea, thiourea and guanidine compounds and their use as anti-viral agents | ELI LILLY AND COMPANY (US) | 1997-11-12 | — | — | EP | disclosed |